Benchmark Results:






Project # completed tree samplings (of 50k trials) # uploaded orthologs avg RF distance( genetree , speciestree ) avg fraction incorrect trees Raw Data
EggNOG 83412262770.0749 +- 0.00400.1541 +- 0.0077
Ensembl Compara (e56) 96732378940.0845 +- 0.00400.1687 +- 0.0075
Ensembl Compara (e81) 109742693120.0871 +- 0.00370.1810 +- 0.0072
Hieranoid 2 100382846480.0585 +- 0.00320.1229 +- 0.0064
InParanoid 119253010140.0547 +- 0.00280.1207 +- 0.0058
InParanoidCore 78082109060.0559 +- 0.00360.1172 +- 0.0071
OMA GETHOGs 84903507220.0562 +- 0.00340.1198 +- 0.0069
OMA GETHOGs 2.0 79027132890.0614 +- 0.00370.1302 +- 0.0074
OMA Groups (RefSet5) 48991761110.0500 +- 0.00440.1017 +- 0.0085
OMA Groups 2.0 63701931440.0508 +- 0.00390.1049 +- 0.0075
OMA Pairs 2.0 90513466870.0577 +- 0.00350.1195 +- 0.0067
PANTHER 8.0 (LDO only) 66662031900.0498 +- 0.00360.1080 +- 0.0075
PANTHER 8.0 (all) 136534091860.0739 +- 0.00300.1637 +- 0.0062
RBH / BBH 92342299650.0672 +- 0.00360.1444 +- 0.0072
RSD 0.8 1e-5 Deluca 88802196460.0699 +- 0.00370.1471 +- 0.0074
SonicParanoid (default) 109093135930.0626 +- 0.00320.1347 +- 0.0064
SonicParanoid (default) CORE 80252103050.0621 +- 0.00380.1296 +- 0.0073
SonicParanoid (fast) 104593026930.0625 +- 0.00320.1359 +- 0.0066
SonicParanoid (fast) CORE 76902058810.0605 +- 0.00370.1298 +- 0.0075
SonicParanoid (ultra-fast) 95142810850.0605 +- 0.00330.1285 +- 0.0067
SonicParanoid (ultra-fast) CORE 67201956660.0613 +- 0.00410.1259 +- 0.0079
metaPhOrs 137023475410.0848 +- 0.00330.1813 +- 0.0065
orthoinspector 1.30 (blast threshold 10-9) 103852688250.0624 +- 0.00330.1329 +- 0.0065
phylomeDB 118663071750.0649 +- 0.00310.1391 +- 0.0062
OMA Pairs (Refset5) 82392723140.0537 +- 0.00340.1140 +- 0.0069



Project # completed tree samplings (of 50k trials) # uploaded orthologs avg RF distance( genetree , speciestree ) avg fraction incorrect trees Raw Data
EggNOG 2062148210.237 +- 0.0130.405 +- 0.021
Ensembl Compara (e56) 1867141520.260 +- 0.0150.436 +- 0.022
Ensembl Compara (e81) 1945143590.251 +- 0.0140.425 +- 0.022
Hieranoid 2 2144152470.228 +- 0.0130.395 +- 0.021
InParanoid 2315164970.241 +- 0.0130.411 +- 0.020
InParanoidCore 1673121230.217 +- 0.0140.380 +- 0.023
OMA GETHOGs 1827136710.227 +- 0.0140.392 +- 0.022
OMA GETHOGs 2.0 1400129540.209 +- 0.0160.363 +- 0.025
OMA Groups (RefSet5) 52966230.194 +- 0.0250.340 +- 0.040
OMA Groups 2.0 94583530.196 +- 0.0180.345 +- 0.030
OMA Pairs 2.0 1524130560.215 +- 0.0150.368 +- 0.024
PANTHER 8.0 (LDO only) 2034113400.243 +- 0.0140.417 +- 0.021
PANTHER 8.0 (all) 2572173380.284 +- 0.0130.465 +- 0.019
RBH / BBH 2210141350.256 +- 0.0130.433 +- 0.021
RSD 0.8 1e-5 Deluca 1945126730.249 +- 0.0140.424 +- 0.022
SonicParanoid (default) 2259156540.237 +- 0.0130.407 +- 0.020
SonicParanoid (default) CORE 1878121370.238 +- 0.0140.412 +- 0.022
SonicParanoid (fast) 1978145950.231 +- 0.0130.398 +- 0.022
SonicParanoid (fast) CORE 1632110880.233 +- 0.0150.406 +- 0.024
SonicParanoid (ultra-fast) 1433116570.203 +- 0.0150.362 +- 0.025
SonicParanoid (ultra-fast) CORE 114986370.201 +- 0.0160.362 +- 0.028
metaPhOrs 2347176120.256 +- 0.0130.427 +- 0.020
orthoinspector 1.30 (blast threshold 10-9) 2208155640.240 +- 0.0130.411 +- 0.021
phylomeDB 2380166260.244 +- 0.0130.417 +- 0.020
OMA Pairs (Refset5) 1314119970.212 +- 0.0160.364 +- 0.026




Project # completed tree samplings (of 50k trials) # uploaded orthologs avg RF distance( genetree , speciestree ) avg fraction incorrect trees Raw Data
EggNOG 221745720740.191 +- 0.0160.207 +- 0.017
Ensembl Compara (e56) 356250867960.224 +- 0.0150.246 +- 0.015
Ensembl Compara (e81) 380658745880.241 +- 0.0150.268 +- 0.016
Hieranoid 2 386263496660.211 +- 0.0140.231 +- 0.015
InParanoid 466184476460.200 +- 0.0140.228 +- 0.015
InParanoidCore 253033554200.176 +- 0.0140.195 +- 0.015
OMA GETHOGs 463980681110.191 +- 0.0140.219 +- 0.015
OMA GETHOGs 2.0 3751202969630.217 +- 0.0140.232 +- 0.015
OMA Groups (RefSet5) 139319230930.167 +- 0.0190.174 +- 0.020
OMA Groups 2.0 202324662740.187 +- 0.0170.196 +- 0.017
OMA Pairs 2.0 388166110630.215 +- 0.0140.230 +- 0.015
PANTHER 8.0 (LDO only) 335833332450.218 +- 0.0140.242 +- 0.015
PANTHER 8.0 (all) 4877108613380.270 +- 0.0150.305 +- 0.016
RBH / BBH 431543007080.209 +- 0.0140.239 +- 0.015
RSD 0.8 1e-5 Deluca 378638165810.200 +- 0.0140.225 +- 0.015
SonicParanoid (default) 437284872240.205 +- 0.0140.233 +- 0.015
SonicParanoid (default) CORE 352435601520.209 +- 0.0140.232 +- 0.015
SonicParanoid (fast) 333176322850.186 +- 0.0130.212 +- 0.015
SonicParanoid (fast) CORE 274231949310.185 +- 0.0140.207 +- 0.015
SonicParanoid (ultra-fast) 167759669200.158 +- 0.0170.181 +- 0.018
SonicParanoid (ultra-fast) CORE 138225243820.130 +- 0.0170.149 +- 0.019
metaPhOrs 284864970490.231 +- 0.0150.259 +- 0.016
orthoinspector 1.30 (blast threshold 10-9) 397454913990.211 +- 0.0140.244 +- 0.015
phylomeDB 304755672080.205 +- 0.0140.225 +- 0.015
OMA Pairs (Refset5) 316347742750.211 +- 0.0140.222 +- 0.015



Project # completed tree samplings (of 50k trials) # uploaded orthologs avg RF distance( genetree , speciestree ) avg fraction incorrect trees Raw Data
EggNOG 418240947360.255 +- 0.0100.537 +- 0.018
Ensembl Compara (e56) 364940816600.252 +- 0.0100.529 +- 0.018
Ensembl Compara (e81) 411047429670.276 +- 0.0110.563 +- 0.018
Hieranoid 2 412255229630.237 +- 0.0100.515 +- 0.018
InParanoid 476368048730.240 +- 0.0100.509 +- 0.018
InParanoidCore 296528824870.231 +- 0.0100.487 +- 0.018
OMA GETHOGs 353465931800.2465 +- 0.00950.546 +- 0.018
OMA GETHOGs 2.0 2863181762000.2194 +- 0.00950.494 +- 0.018
OMA Groups (RefSet5) 75617080100.176 +- 0.0170.402 +- 0.035
OMA Groups 2.0 123621342530.197 +- 0.0140.444 +- 0.028
OMA Pairs 2.0 251358211050.224 +- 0.0100.496 +- 0.020
PANTHER 8.0 (LDO only) 476928158510.251 +- 0.0100.527 +- 0.018
PANTHER 8.0 (all) 672489056220.299 +- 0.0110.580 +- 0.018
RBH / BBH 526534342600.247 +- 0.0100.529 +- 0.018
RSD 0.8 1e-5 Deluca 444630884320.250 +- 0.0100.525 +- 0.018
SonicParanoid (default) 500668791190.245 +- 0.0100.523 +- 0.018
SonicParanoid (default) CORE 410128828700.248 +- 0.0100.518 +- 0.018
SonicParanoid (fast) 418864330920.235 +- 0.0100.510 +- 0.018
SonicParanoid (fast) CORE 337926805350.240 +- 0.0100.499 +- 0.018
SonicParanoid (ultra-fast) 259454166420.233 +- 0.0100.514 +- 0.019
SonicParanoid (ultra-fast) CORE 218422496120.233 +- 0.0110.501 +- 0.021
metaPhOrs 354156761080.269 +- 0.0100.550 +- 0.018
orthoinspector 1.30 (blast threshold 10-9) 493145815770.255 +- 0.0100.547 +- 0.018
phylomeDB 337047299650.248 +- 0.0100.518 +- 0.018
OMA Pairs (Refset5) 227441547560.215 +- 0.0110.478 +- 0.021



Project # completed tree samplings (of 50k trials) # uploaded orthologs avg RF distance( genetree , speciestree ) avg fraction incorrect trees Raw Data
EggNOG 1439710971100.1977 +- 0.00690.678 +- 0.017
Ensembl Compara (e56) 1207111576750.1993 +- 0.00690.681 +- 0.017
Ensembl Compara (e81) 1346612466140.2091 +- 0.00730.694 +- 0.016
Hieranoid 2 1186812375080.1899 +- 0.00690.659 +- 0.017
InParanoid 1224214370550.2000 +- 0.00710.687 +- 0.017
InParanoidCore 89569476370.1649 +- 0.00620.623 +- 0.017
OMA GETHOGs 1154923684990.2057 +- 0.00710.689 +- 0.017
OMA GETHOGs 2.0 1121254029400.2061 +- 0.00770.666 +- 0.017
OMA Groups (RefSet5) 61458399880.1803 +- 0.00690.629 +- 0.017
OMA Groups 2.0 75709075480.1764 +- 0.00700.617 +- 0.017
OMA Pairs 2.0 1110424630850.1999 +- 0.00740.661 +- 0.017
PANTHER 8.0 (LDO only) 97409030110.1820 +- 0.00680.642 +- 0.017
PANTHER 8.0 (all) 1346417797710.2177 +- 0.00750.695 +- 0.016
RBH / BBH 1397210341290.1985 +- 0.00710.673 +- 0.017
RSD 0.8 1e-5 Deluca 1373010169750.1990 +- 0.00700.686 +- 0.017
SonicParanoid (default) 1424414393540.1889 +- 0.00690.652 +- 0.017
SonicParanoid (default) CORE 123159662190.1887 +- 0.00700.655 +- 0.017
SonicParanoid (fast) 1406314343420.1989 +- 0.00700.671 +- 0.017
SonicParanoid (fast) CORE 120579617050.1866 +- 0.00670.657 +- 0.017
SonicParanoid (ultra-fast) 1334914364170.1978 +- 0.00700.678 +- 0.017
SonicParanoid (ultra-fast) CORE 115869441400.1881 +- 0.00660.676 +- 0.017
metaPhOrs 1740215959180.2081 +- 0.00720.684 +- 0.017
orthoinspector 1.30 (blast threshold 10-9) 1524211752780.1966 +- 0.00690.674 +- 0.017
phylomeDB 1261813854180.1925 +- 0.00670.679 +- 0.017
OMA Pairs (Refset5) 1023917410900.2015 +- 0.00740.669 +- 0.017



Project # completed tree samplings (of 50k trials) # uploaded orthologs avg RF distance( genetree , speciestree ) avg fraction incorrect trees Raw Data
EggNOG 147821653690.079 +- 0.0100.079 +- 0.010
Ensembl Compara (e56) 148921788450.085 +- 0.0100.085 +- 0.010
Ensembl Compara (e81) 151221816050.094 +- 0.0100.094 +- 0.010
Hieranoid 2 152011756360.079 +- 0.0100.079 +- 0.010
InParanoid 164811898160.077 +- 0.0100.077 +- 0.010
InParanoidCore 135331454700.0607 +- 0.00850.0607 +- 0.0085
OMA GETHOGs 111301618830.0640 +- 0.00880.0640 +- 0.0088
OMA GETHOGs 2.0 89001461600.0597 +- 0.00850.0597 +- 0.0085
OMA Groups (RefSet5) 3584789520.0403 +- 0.00700.0403 +- 0.0070
OMA Groups 2.0 62911015790.0507 +- 0.00780.0507 +- 0.0078
OMA Pairs 2.0 99321474100.0627 +- 0.00870.0627 +- 0.0087
PANTHER 8.0 (LDO only) 156701406090.0753 +- 0.00940.0753 +- 0.0094
PANTHER 8.0 (all) 186272144650.108 +- 0.0110.108 +- 0.011
RBH / BBH 183041777500.095 +- 0.0100.095 +- 0.010
RSD 0.8 1e-5 Deluca 166081658510.0737 +- 0.00930.0737 +- 0.0093
SonicParanoid (default) 168121862750.0717 +- 0.00920.0717 +- 0.0092
SonicParanoid (default) CORE 156321574670.0737 +- 0.00930.0737 +- 0.0093
SonicParanoid (fast) 150491720640.078 +- 0.0100.078 +- 0.010
SonicParanoid (fast) CORE 137771454120.0693 +- 0.00910.0693 +- 0.0091
SonicParanoid (ultra-fast) 107941359370.0650 +- 0.00880.0650 +- 0.0088
SonicParanoid (ultra-fast) CORE 100581155400.0667 +- 0.00890.0667 +- 0.0089
metaPhOrs 155811778110.081 +- 0.0100.081 +- 0.010
orthoinspector 1.30 (blast threshold 10-9) 168251834750.083 +- 0.0100.083 +- 0.010
phylomeDB 162991878760.0707 +- 0.00920.0707 +- 0.0092
OMA Pairs (Refset5) 87781355980.0637 +- 0.00870.0637 +- 0.0087



Case Project pos. predictive value rate true positive rate Raw Data
APPEggNOG 0.913 +- 0.1628560.2442 +- 0.128407
 Ensembl Compara (e56) 0.9767 +- 0.04504850.9767 +- 0.0450485
 Ensembl Compara (e81) 0.9459 +- 0.1030430.407 +- 0.146839
 Hieranoid 2 0.9452 +- 0.07383140.8023 +- 0.119034
 InParanoid 0.9683 +- 0.06122670.7093 +- 0.135725
 InParanoidCore 0.9487 +- 0.09790160.4302 +- 0.147987
 OMA GETHOGs 0.9701 +- 0.05762770.7558 +- 0.128407
 OMA GETHOGs 2.0 0.9655 +- 0.06641070.6512 +- 0.142455
 OMA Groups (RefSet5) 0.9167 +- 0.156380.2558 +- 0.130414
 OMA Groups 2.0 0.931 +- 0.1304280.314 +- 0.138717
 OMA Pairs 2.0 0.9649 +- 0.06755460.6395 +- 0.143511
 PANTHER 8.0 (LDO only) 0.9487 +- 0.09790160.4302 +- 0.147987
 PANTHER 8.0 (all) 0.9718 +- 0.0544280.8023 +- 0.119034
 RBH / BBH 0.9512 +- 0.09324860.4535 +- 0.148801
 RSD 0.8 1e-5 Deluca 0.931 +- 0.1304280.314 +- 0.138717
 SonicParanoid (default) 0.9756 +- 0.04721810.9302 +- 0.0761454
 SonicParanoid (default) CORE 0.95 +- 0.09551860.4419 +- 0.148435
 SonicParanoid (fast) 0.9756 +- 0.04721810.9302 +- 0.0761454
 SonicParanoid (fast) CORE 0.95 +- 0.09551860.4419 +- 0.148435
 SonicParanoid (ultra-fast) 0.975 +- 0.04838380.907 +- 0.0868192
 SonicParanoid (ultra-fast) CORE 0.9487 +- 0.09790160.4302 +- 0.147987
 metaPhOrs 0.971 +- 0.05598230.7791 +- 0.124005
 orthoinspector 1.30 (blast threshold 10-9) 0.9688 +- 0.06028520.7209 +- 0.134068
 phylomeDB 0.9706 +- 0.0567930.7674 +- 0.126273
 OMA Pairs (Refset5) 0.96 +- 0.0768160.5581 +- 0.148435
ASTEREggNOG 0.9845 +- 0.03015090.386 +- 0.0743969
 Ensembl Compara (e56) 0.9835 +- 0.03212790.3617 +- 0.0734278
 Ensembl Compara (e81) 0.9845 +- 0.03015090.386 +- 0.0743969
 Hieranoid 2 0.9892 +- 0.02107430.5562 +- 0.0759241
 InParanoid 0.9886 +- 0.02227170.5258 +- 0.0763067
 InParanoidCore 0.9841 +- 0.0308630.3769 +- 0.0740569
 OMA GETHOGs 0.989 +- 0.02153770.5441 +- 0.0761114
 OMA GETHOGs 2.0 0.9845 +- 0.03015090.386 +- 0.0743969
 OMA Groups (RefSet5) 0.9825 +- 0.03408320.3404 +- 0.0724129
 OMA Groups 2.0 0.9825 +- 0.03408320.3404 +- 0.0724129
 OMA Pairs 2.0 0.9853 +- 0.02861060.4073 +- 0.0750839
 PANTHER 8.0 (LDO only) 0.989 +- 0.02153770.5441 +- 0.0761114
 PANTHER 8.0 (all) 0.989 +- 0.02153770.5441 +- 0.0761114
 RBH / BBH 0.9898 +- 0.0197970.5927 +- 0.0750839
 RSD 0.8 1e-5 Deluca 0.9868 +- 0.0257880.4529 +- 0.0760687
 SonicParanoid (default) 0.988 +- 0.02333220.5015 +- 0.0764083
 SonicParanoid (default) CORE 0.9876 +- 0.02419630.4833 +- 0.0763661
 SonicParanoid (fast) 0.9853 +- 0.02861060.4073 +- 0.0750839
 SonicParanoid (fast) CORE 0.9853 +- 0.02861060.4073 +- 0.0750839
 SonicParanoid (ultra-fast) 0.9845 +- 0.03015090.386 +- 0.0743969
 SonicParanoid (ultra-fast) CORE 0.9845 +- 0.03015090.386 +- 0.0743969
 metaPhOrs 0.9864 +- 0.02648470.4407 +- 0.07587
 orthoinspector 1.30 (blast threshold 10-9) 0.9845 +- 0.03015090.386 +- 0.0743969
 phylomeDB 0.9877 +- 0.02390080.4894 +- 0.0763915
 OMA Pairs (Refset5) 0.9853 +- 0.02861060.4073 +- 0.0750839
BAMBIEggNOG 0.9759 +- 0.04665620.757 +- 0.114928
 Ensembl Compara (e56) 0.963 +- 0.05816350.729 +- 0.119108
 Ensembl Compara (e81) 0.9571 +- 0.06709990.6262 +- 0.129647
 Hieranoid 2 0.9714 +- 0.05519410.6355 +- 0.128968
 InParanoid 0.9714 +- 0.05519410.6355 +- 0.128968
 InParanoidCore 0.9661 +- 0.06530480.5327 +- 0.133696
 OMA GETHOGs 0.975 +- 0.04838380.729 +- 0.119108
 OMA GETHOGs 2.0 0.9714 +- 0.05519410.6355 +- 0.128968
 OMA Groups (RefSet5) 0.9714 +- 0.05519410.6355 +- 0.128968
 OMA Groups 2.0 0.9714 +- 0.05519410.6355 +- 0.128968
 OMA Pairs 2.0 0.974 +- 0.05024370.7009 +- 0.122688
 PANTHER 8.0 (LDO only) 0.9756 +- 0.04721810.7477 +- 0.116392
 PANTHER 8.0 (all) 0.9681 +- 0.05025290.8505 +- 0.09556
 RBH / BBH 0.9783 +- 0.04214320.8411 +- 0.0979582
 RSD 0.8 1e-5 Deluca 0.9747 +- 0.04898820.7196 +- 0.120365
 SonicParanoid (default) 0.9762 +- 0.04610790.7664 +- 0.113389
 SonicParanoid (default) CORE 0.9759 +- 0.04665620.757 +- 0.114928
 SonicParanoid (fast) 0.9762 +- 0.04610790.7664 +- 0.113389
 SonicParanoid (fast) CORE 0.9759 +- 0.04665620.757 +- 0.114928
 SonicParanoid (ultra-fast) 0.9759 +- 0.04665620.757 +- 0.114928
 SonicParanoid (ultra-fast) CORE 0.9756 +- 0.04721810.7477 +- 0.116392
 metaPhOrs 0.9744 +- 0.04960780.7103 +- 0.121558
 orthoinspector 1.30 (blast threshold 10-9) 0.9756 +- 0.04721810.7477 +- 0.116392
 phylomeDB 0.9759 +- 0.04665620.757 +- 0.114928
 OMA Pairs (Refset5) 0.974 +- 0.05024370.7009 +- 0.122688
BAREggNOG 0.9878 +- 0.02375650.4894 +- 0.0761606
 Ensembl Compara (e56) 0.9923 +- 0.01496150.7825 +- 0.0628558
 Ensembl Compara (e81) 0.9911 +- 0.01734460.6737 +- 0.071432
 Hieranoid 2 0.9916 +- 0.01647020.71 +- 0.0691352
 InParanoid 0.8178 +- 0.06523060.6647 +- 0.0719285
 InParanoidCore 0.947 +- 0.05406470.3776 +- 0.0738613
 OMA GETHOGs 0.9533 +- 0.03647920.7402 +- 0.066813
 OMA GETHOGs 2.0 0.9358 +- 0.04967280.5287 +- 0.076052
 OMA Groups (RefSet5) 0.9688 +- 0.04262810.3746 +- 0.0737437
 OMA Groups 2.0 0.9701 +- 0.04074870.3927 +- 0.0744044
 OMA Pairs 2.0 0.94 +- 0.04654740.568 +- 0.0754702
 PANTHER 8.0 (LDO only) 0.99 +- 0.01950180.5982 +- 0.0746943
 PANTHER 8.0 (all) 0.5772 +- 0.0688970.6888 +- 0.0705366
 RBH / BBH 0.7792 +- 0.07421860.565 +- 0.075532
 RSD 0.8 1e-5 Deluca 0.8313 +- 0.0665930.6103 +- 0.0743018
 SonicParanoid (default) 0.9526 +- 0.04271720.5468 +- 0.0758426
 SonicParanoid (default) CORE 0.9704 +- 0.03612840.4955 +- 0.0761744
 SonicParanoid (fast) 0.9832 +- 0.03266330.3535 +- 0.0728332
 SonicParanoid (fast) CORE 0.9806 +- 0.03768710.3051 +- 0.0701543
 SonicParanoid (ultra-fast) 0.9775 +- 0.04354730.2628 +- 0.0670632
 SonicParanoid (ultra-fast) CORE 0.9747 +- 0.04898820.2326 +- 0.064371
 metaPhOrs 0.9829 +- 0.02097290.8701 +- 0.0512224
 orthoinspector 1.30 (blast threshold 10-9) 0.83 +- 0.06545370.6344 +- 0.0733721
 phylomeDB 0.9921 +- 0.01549370.7553 +- 0.0655001
 OMA Pairs (Refset5) 0.9388 +- 0.04746640.5559 +- 0.0757002
CASPEggNOG 0.5 +- 0.6929650.5 +- 0.692965
 Ensembl Compara (e56) 0.5 +- 0.6929650.5 +- 0.692965
 Ensembl Compara (e81) 0.5 +- 0.6929650.5 +- 0.692965
 Hieranoid 2 0.5 +- 0.6929650.5 +- 0.692965
 InParanoid 0.5 +- 0.6929650.5 +- 0.692965
 InParanoidCore 0.5 +- 0.6929650.5 +- 0.692965
 OMA GETHOGs 0.5 +- 0.6929650.5 +- 0.692965
 OMA GETHOGs 2.0 0.5 +- 0.6929650.5 +- 0.692965
 OMA Groups (RefSet5) 0.5 +- 0.6929650.5 +- 0.692965
 OMA Groups 2.0 0.5 +- 0.6929650.5 +- 0.692965
 OMA Pairs 2.0 0.5 +- 0.6929650.5 +- 0.692965
 PANTHER 8.0 (LDO only) 0.5 +- 0.6929650.5 +- 0.692965
 PANTHER 8.0 (all) 0.5 +- 0.6929650.5 +- 0.692965
 RBH / BBH 0.5 +- 0.6929650.5 +- 0.692965
 RSD 0.8 1e-5 Deluca 0.5 +- 0.6929650.5 +- 0.692965
 SonicParanoid (default) 0.5 +- 0.6929650.5 +- 0.692965
 SonicParanoid (default) CORE 0.5 +- 0.6929650.5 +- 0.692965
 SonicParanoid (fast) 0.5 +- 0.6929650.5 +- 0.692965
 SonicParanoid (fast) CORE 0.5 +- 0.6929650.5 +- 0.692965
 SonicParanoid (ultra-fast) 0.5 +- 0.6929650.5 +- 0.692965
 SonicParanoid (ultra-fast) CORE 0.5 +- 0.6929650.5 +- 0.692965
 metaPhOrs 0.5 +- 0.6929650.5 +- 0.692965
 orthoinspector 1.30 (blast threshold 10-9) 0.5 +- 0.6929650.5 +- 0.692965
 phylomeDB 0.5 +- 0.6929650.5 +- 0.692965
 OMA Pairs (Refset5) 0.5 +- 0.6929650.5 +- 0.692965
CITEEggNOG 0.931 +- 0.1304280.4154 +- 0.169424
 Ensembl Compara (e56) 0.8 +- 0.1495030.6769 +- 0.160782
 Ensembl Compara (e81) 0.6053 +- 0.2197890.3538 +- 0.164395
 Hieranoid 2 0.9394 +- 0.1151320.4769 +- 0.17172
 InParanoid 0.9412 +- 0.1118520.4923 +- 0.171883
 InParanoidCore 0.9167 +- 0.156380.3385 +- 0.162685
 OMA GETHOGs 0.9412 +- 0.1118520.4923 +- 0.171883
 OMA GETHOGs 2.0 0.92 +- 0.1503970.3538 +- 0.164395
 OMA Groups (RefSet5) 0.9167 +- 0.156380.3385 +- 0.162685
 OMA Groups 2.0 0.9167 +- 0.156380.3385 +- 0.162685
 OMA Pairs 2.0 0.9231 +- 0.1448540.3692 +- 0.16592
 PANTHER 8.0 (LDO only) 0.9429 +- 0.1087530.5077 +- 0.171883
 PANTHER 8.0 (all) 0.9592 +- 0.07835020.7231 +- 0.153846
 RBH / BBH 0.9412 +- 0.1118520.4923 +- 0.171883
 RSD 0.8 1e-5 Deluca 0.9333 +- 0.1262360.4308 +- 0.170248
 SonicParanoid (default) 0.9394 +- 0.1151320.4769 +- 0.17172
 SonicParanoid (default) CORE 0.931 +- 0.1304280.4154 +- 0.169424
 SonicParanoid (fast) 0.9394 +- 0.1151320.4769 +- 0.17172
 SonicParanoid (fast) CORE 0.931 +- 0.1304280.4154 +- 0.169424
 SonicParanoid (ultra-fast) 0.9429 +- 0.1087530.5077 +- 0.171883
 SonicParanoid (ultra-fast) CORE 0.9333 +- 0.1262360.4308 +- 0.170248
 metaPhOrs 0.9565 +- 0.08334430.6769 +- 0.160782
 orthoinspector 1.30 (blast threshold 10-9) 0.92 +- 0.1503970.3538 +- 0.164395
 phylomeDB 0.92 +- 0.1503970.3538 +- 0.164395
 OMA Pairs (Refset5) 0.9231 +- 0.1448540.3692 +- 0.16592
ClusterinEggNOG 0.8462 +- 0.2773750.8462 +- 0.277375
 Ensembl Compara (e56) 0.8462 +- 0.2773750.8462 +- 0.277375
 Ensembl Compara (e81) 0.8462 +- 0.2773750.8462 +- 0.277375
 Hieranoid 2 0.8462 +- 0.2773750.8462 +- 0.277375
 InParanoid 0.8462 +- 0.2773750.8462 +- 0.277375
 InParanoidCore 0.8462 +- 0.2773750.8462 +- 0.277375
 OMA GETHOGs 0.8462 +- 0.2773750.8462 +- 0.277375
 OMA GETHOGs 2.0 0.8462 +- 0.2773750.8462 +- 0.277375
 OMA Groups (RefSet5) 0.8462 +- 0.2773750.8462 +- 0.277375
 OMA Groups 2.0 0.8462 +- 0.2773750.8462 +- 0.277375
 OMA Pairs 2.0 0.8462 +- 0.2773750.8462 +- 0.277375
 PANTHER 8.0 (LDO only) 0.8462 +- 0.2773750.8462 +- 0.277375
 PANTHER 8.0 (all) 0.8462 +- 0.2773750.8462 +- 0.277375
 RBH / BBH 0.8462 +- 0.2773750.8462 +- 0.277375
 RSD 0.8 1e-5 Deluca 0.8462 +- 0.2773750.8462 +- 0.277375
 SonicParanoid (default) 0.8462 +- 0.2773750.8462 +- 0.277375
 SonicParanoid (default) CORE 0.8462 +- 0.2773750.8462 +- 0.277375
 SonicParanoid (fast) 0.8462 +- 0.2773750.8462 +- 0.277375
 SonicParanoid (fast) CORE 0.8462 +- 0.2773750.8462 +- 0.277375
 SonicParanoid (ultra-fast) 0.8182 +- 0.3223430.6923 +- 0.354819
 SonicParanoid (ultra-fast) CORE 0.8182 +- 0.3223430.6923 +- 0.354819
 metaPhOrs 0.8462 +- 0.2773750.8462 +- 0.277375
 orthoinspector 1.30 (blast threshold 10-9) 0.8462 +- 0.2773750.8462 +- 0.277375
 phylomeDB 0.8182 +- 0.3223430.6923 +- 0.354819
 OMA Pairs (Refset5) 0.8462 +- 0.2773750.8462 +- 0.277375
GH14EggNOG 0.5 +- 0.6929650.5 +- 0.692965
 Ensembl Compara (e56) 0.5 +- 0.6929650.5 +- 0.692965
 Ensembl Compara (e81) 0.5 +- 0.6929650.5 +- 0.692965
 Hieranoid 2 0.5 +- 0.6929650.5 +- 0.692965
 InParanoid 0.5 +- 0.6929650.5 +- 0.692965
 InParanoidCore 0.5 +- 0.6929650.5 +- 0.692965
 OMA GETHOGs 0.5 +- 0.6929650.5 +- 0.692965
 OMA GETHOGs 2.0 0.5 +- 0.6929650.5 +- 0.692965
 OMA Groups (RefSet5) 0.5 +- 0.6929650.5 +- 0.692965
 OMA Groups 2.0 0.5 +- 0.6929650.5 +- 0.692965
 OMA Pairs 2.0 0.5 +- 0.6929650.5 +- 0.692965
 PANTHER 8.0 (LDO only) 0.5 +- 0.6929650.5 +- 0.692965
 PANTHER 8.0 (all) 0.5 +- 0.6929650.5 +- 0.692965
 RBH / BBH 0.5 +- 0.6929650.5 +- 0.692965
 RSD 0.8 1e-5 Deluca 0.5 +- 0.6929650.5 +- 0.692965
 SonicParanoid (default) 0.5 +- 0.6929650.5 +- 0.692965
 SonicParanoid (default) CORE 0.5 +- 0.6929650.5 +- 0.692965
 SonicParanoid (fast) 0.5 +- 0.6929650.5 +- 0.692965
 SonicParanoid (fast) CORE 0.5 +- 0.6929650.5 +- 0.692965
 SonicParanoid (ultra-fast) 0.5 +- 0.6929650.5 +- 0.692965
 SonicParanoid (ultra-fast) CORE 0.5 +- 0.6929650.5 +- 0.692965
 metaPhOrs 0.5 +- 0.6929650.5 +- 0.692965
 orthoinspector 1.30 (blast threshold 10-9) 0.5 +- 0.6929650.5 +- 0.692965
 phylomeDB 0.5 +- 0.6929650.5 +- 0.692965
 OMA Pairs (Refset5) 0.5 +- 0.6929650.5 +- 0.692965
HOXEggNOG 0.9124 +- 0.06694770.448 +- 0.0825239
 Ensembl Compara (e56) 0.1975 +- 0.08670510.1147 +- 0.0528797
 Ensembl Compara (e81) 0.5455 +- 0.1154170.2796 +- 0.0744748
 Hieranoid 2 0.86 +- 0.09617990.3082 +- 0.076629
 InParanoid 0.9138 +- 0.07223310.3799 +- 0.0805455
 InParanoidCore 0.9359 +- 0.07687320.2616 +- 0.0729391
 OMA GETHOGs 0.5854 +- 0.1066340.3441 +- 0.0788364
 OMA GETHOGs 2.0 0.8091 +- 0.1038690.319 +- 0.0773458
 OMA Groups (RefSet5) 0.918 +- 0.09735440.2007 +- 0.0664677
 OMA Groups 2.0 0.9091 +- 0.09808580.2151 +- 0.068181
 OMA Pairs 2.0 0.8037 +- 0.1064280.3082 +- 0.076629
 PANTHER 8.0 (LDO only) 0.9344 +- 0.08785040.2043 +- 0.0669081
 PANTHER 8.0 (all) 0.4529 +- 0.07482890.552 +- 0.0825239
 RBH / BBH 0.9381 +- 0.06285740.3799 +- 0.0805455
 RSD 0.8 1e-5 Deluca 0.9368 +- 0.06917610.319 +- 0.0773458
 SonicParanoid (default) 0.9231 +- 0.05681670.5591 +- 0.0823909
 SonicParanoid (default) CORE 0.9519 +- 0.05814660.3548 +- 0.0793996
 SonicParanoid (fast) 0.9231 +- 0.05681670.5591 +- 0.0823909
 SonicParanoid (fast) CORE 0.9519 +- 0.05814660.3548 +- 0.0793996
 SonicParanoid (ultra-fast) 0.9357 +- 0.05200360.5735 +- 0.0820725
 SonicParanoid (ultra-fast) CORE 0.9524 +- 0.05760670.3584 +- 0.0795777
 metaPhOrs 0.8905 +- 0.06104010.6416 +- 0.0795777
 orthoinspector 1.30 (blast threshold 10-9) 0.8246 +- 0.08062080.5054 +- 0.0829687
 phylomeDB 0.9109 +- 0.07857860.3297 +- 0.0780151
 OMA Pairs (Refset5) 0.8333 +- 0.1022830.3047 +- 0.0763792
MAPTEggNOG 0.7778 +- 0.3841240.7778 +- 0.384124
 Ensembl Compara (e56) 0.7778 +- 0.3841240.7778 +- 0.384124
 Ensembl Compara (e81) 0.7778 +- 0.3841240.7778 +- 0.384124
 Hieranoid 2 0.7778 +- 0.3841240.7778 +- 0.384124
 InParanoid 0.7778 +- 0.3841240.7778 +- 0.384124
 InParanoidCore 0.7778 +- 0.3841240.7778 +- 0.384124
 OMA GETHOGs 0.7778 +- 0.3841240.7778 +- 0.384124
 OMA GETHOGs 2.0 0.7778 +- 0.3841240.7778 +- 0.384124
 OMA Groups (RefSet5) 0.75 +- 0.4243520.6667 +- 0.435556
 OMA Groups 2.0 0.75 +- 0.4243520.6667 +- 0.435556
 OMA Pairs 2.0 0.7778 +- 0.3841240.7778 +- 0.384124
 PANTHER 8.0 (LDO only) 0.7778 +- 0.3841240.7778 +- 0.384124
 PANTHER 8.0 (all) 0.7778 +- 0.3841240.7778 +- 0.384124
 RBH / BBH 0.7778 +- 0.3841240.7778 +- 0.384124
 RSD 0.8 1e-5 Deluca 0.7778 +- 0.3841240.7778 +- 0.384124
 SonicParanoid (default) 0.7778 +- 0.3841240.7778 +- 0.384124
 SonicParanoid (default) CORE 0.7778 +- 0.3841240.7778 +- 0.384124
 SonicParanoid (fast) 0.7778 +- 0.3841240.7778 +- 0.384124
 SonicParanoid (fast) CORE 0.7778 +- 0.3841240.7778 +- 0.384124
 SonicParanoid (ultra-fast) 0.7778 +- 0.3841240.7778 +- 0.384124
 SonicParanoid (ultra-fast) CORE 0.7778 +- 0.3841240.7778 +- 0.384124
 metaPhOrs 0.7778 +- 0.3841240.7778 +- 0.384124
 orthoinspector 1.30 (blast threshold 10-9) 0.7778 +- 0.3841240.7778 +- 0.384124
 phylomeDB 0.75 +- 0.4243520.6667 +- 0.435556
 OMA Pairs (Refset5) 0.7778 +- 0.3841240.7778 +- 0.384124
NOXEggNOG 0.995 +- 0.009678910.704 +- 0.0529508
 Ensembl Compara (e56) 0.875 +- 0.0582110.38 +- 0.0563052
 Ensembl Compara (e81) 0.8711 +- 0.04972530.5324 +- 0.0578774
 Hieranoid 2 0.8692 +- 0.04010250.8266 +- 0.0439141
 InParanoid 0.9387 +- 0.03291170.6708 +- 0.0545123
 InParanoidCore 0.9921 +- 0.01549370.4378 +- 0.0575493
 OMA GETHOGs 0.8662 +- 0.03858610.9072 +- 0.0336607
 OMA GETHOGs 2.0 0.9954 +- 0.009011520.7566 +- 0.0497813
 OMA Groups (RefSet5) 0.9919 +- 0.0158060.4291 +- 0.0574129
 OMA Groups 2.0 0.9933 +- 0.01306650.5201 +- 0.0579524
 OMA Pairs 2.0 0.9544 +- 0.02691840.7706 +- 0.0487729
 PANTHER 8.0 (LDO only) 0.8992 +- 0.05194850.4063 +- 0.056972
 PANTHER 8.0 (all) 0.8173 +- 0.04250350.9089 +- 0.0333736
 RBH / BBH 0.9895 +- 0.01675670.4939 +- 0.0579951
 RSD 0.8 1e-5 Deluca 0.9897 +- 0.01646940.5026 +- 0.0579985
 SonicParanoid (default) 0.9353 +- 0.03340290.683 +- 0.0539744
 SonicParanoid (default) CORE 0.9927 +- 0.01425420.4764 +- 0.0579345
 SonicParanoid (fast) 0.9353 +- 0.03340290.683 +- 0.0539744
 SonicParanoid (fast) CORE 0.9927 +- 0.01425420.4764 +- 0.0579345
 SonicParanoid (ultra-fast) 0.9721 +- 0.02300480.6708 +- 0.0545123
 SonicParanoid (ultra-fast) CORE 0.9777 +- 0.02495750.4606 +- 0.057819
 metaPhOrs 0.9964 +- 0.007088590.9632 +- 0.0218327
 orthoinspector 1.30 (blast threshold 10-9) 0.9427 +- 0.0291230.8074 +- 0.045747
 phylomeDB 0.9962 +- 0.00749530.9107 +- 0.0330828
 OMA Pairs (Refset5) 0.9669 +- 0.02410960.7163 +- 0.052292
POPEggNOG 0.986 +- 0.027220.6845 +- 0.0897505
 Ensembl Compara (e56) 0.9885 +- 0.02239890.835 +- 0.0716926
 Ensembl Compara (e81) 0.841 +- 0.07258090.7961 +- 0.0778066
 Hieranoid 2 0.9891 +- 0.0211880.8835 +- 0.0619599
 InParanoid 0.9701 +- 0.03327150.9466 +- 0.0434192
 InParanoidCore 0.9684 +- 0.0351660.8932 +- 0.0596472
 OMA GETHOGs 0.989 +- 0.02141970.8738 +- 0.0641348
 OMA GETHOGs 2.0 0.9883 +- 0.02278920.8204 +- 0.0741336
 OMA Groups (RefSet5) 0.9858 +- 0.02760330.6748 +- 0.0904722
 OMA Groups 2.0 0.9877 +- 0.02404740.7767 +- 0.0804283
 OMA Pairs 2.0 0.9882 +- 0.02292280.8155 +- 0.0749061
 PANTHER 8.0 (LDO only) 0.9897 +- 0.01999970.9369 +- 0.0469591
 PANTHER 8.0 (all) 0.9903 +- 0.01893650.9903 +- 0.0189365
 RBH / BBH 0.9837 +- 0.02587870.8786 +- 0.0630636
 RSD 0.8 1e-5 Deluca 0.9838 +- 0.02574030.8835 +- 0.0619599
 SonicParanoid (default) 0.9757 +- 0.02972030.9757 +- 0.0297203
 SonicParanoid (default) CORE 0.9784 +- 0.02964010.8786 +- 0.0630636
 SonicParanoid (fast) 0.9757 +- 0.02972030.9757 +- 0.0297203
 SonicParanoid (fast) CORE 0.9784 +- 0.02964010.8786 +- 0.0630636
 SonicParanoid (ultra-fast) 0.9737 +- 0.03218940.8981 +- 0.058434
 SonicParanoid (ultra-fast) CORE 0.9769 +- 0.0316720.8204 +- 0.0741336
 metaPhOrs 0.9848 +- 0.02406330.9466 +- 0.0434192
 orthoinspector 1.30 (blast threshold 10-9) 0.9614 +- 0.03713510.966 +- 0.0349903
 phylomeDB 0.9882 +- 0.02292280.8155 +- 0.0749061
 OMA Pairs (Refset5) 0.9878 +- 0.02375650.7864 +- 0.0791505
PSENEggNOG 0.9897 +- 0.01999970.9847 +- 0.0243064
 Ensembl Compara (e56) 0.9873 +- 0.02465240.7959 +- 0.0797956
 Ensembl Compara (e81) 0.9897 +- 0.01999970.9847 +- 0.0243064
 Hieranoid 2 0.9886 +- 0.02214540.8878 +- 0.0624991
 InParanoid 0.9867 +- 0.02595870.7551 +- 0.085141
 InParanoidCore 0.9796 +- 0.03958960.4898 +- 0.0989744
 OMA GETHOGs 0.9886 +- 0.02214540.8878 +- 0.0624991
 OMA GETHOGs 2.0 0.9886 +- 0.02214540.8878 +- 0.0624991
 OMA Groups (RefSet5) 0.9474 +- 0.1004070.1837 +- 0.0766651
 OMA Groups 2.0 0.971 +- 0.05598230.3418 +- 0.0939116
 OMA Pairs 2.0 0.9855 +- 0.02819950.6939 +- 0.0912497
 PANTHER 8.0 (LDO only) 0.975 +- 0.04838380.398 +- 0.0969114
 PANTHER 8.0 (all) 0.9886 +- 0.02214540.8878 +- 0.0624991
 RBH / BBH 0.982 +- 0.03499570.5561 +- 0.0983694
 RSD 0.8 1e-5 Deluca 0.9817 +- 0.03563160.5459 +- 0.0985767
 SonicParanoid (default) 0.9886 +- 0.02214540.8878 +- 0.0624991
 SonicParanoid (default) CORE 0.9802 +- 0.03842550.5051 +- 0.0989897
 SonicParanoid (fast) 0.9886 +- 0.02214540.8878 +- 0.0624991
 SonicParanoid (fast) CORE 0.9802 +- 0.03842550.5051 +- 0.0989897
 SonicParanoid (ultra-fast) 0.9835 +- 0.03212790.6071 +- 0.0966954
 SonicParanoid (ultra-fast) CORE 0.973 +- 0.05225230.3673 +- 0.0954474
 metaPhOrs 0.9878 +- 0.02375650.8265 +- 0.0749694
 orthoinspector 1.30 (blast threshold 10-9) 0.9889 +- 0.02165690.9082 +- 0.0571786
 phylomeDB 0.9877 +- 0.02390080.8214 +- 0.0758287
 OMA Pairs (Refset5) 0.9826 +- 0.03378940.5765 +- 0.0978285
RPSEggNOG 0.92 +- 0.1503970.5 +- 0.204344
 Ensembl Compara (e56) 0.92 +- 0.1503970.5 +- 0.204344
 Ensembl Compara (e81) 0.92 +- 0.1503970.5 +- 0.204344
 Hieranoid 2 0.9091 +- 0.169890.4348 +- 0.202598
 InParanoid 0.9444 +- 0.1058210.7391 +- 0.179459
 InParanoidCore 0.8462 +- 0.2773750.2391 +- 0.174327
 OMA GETHOGs 0.9565 +- 0.08334430.9565 +- 0.0833443
 OMA GETHOGs 2.0 0.92 +- 0.1503970.5 +- 0.204344
 OMA Groups (RefSet5) 0.8824 +- 0.21660.3261 +- 0.191585
 OMA Groups 2.0 0.8824 +- 0.21660.3261 +- 0.191585
 OMA Pairs 2.0 0.9355 +- 0.1223040.6304 +- 0.197269
 PANTHER 8.0 (LDO only) 0.9048 +- 0.1775550.413 +- 0.20123
 PANTHER 8.0 (all) 0.9565 +- 0.08334430.9565 +- 0.0833443
 RBH / BBH 0.9394 +- 0.1151320.6739 +- 0.191585
 RSD 0.8 1e-5 Deluca 0.9394 +- 0.1151320.6739 +- 0.191585
 SonicParanoid (default) 0.9375 +- 0.118610.6522 +- 0.19465
 SonicParanoid (default) CORE 0.9167 +- 0.156380.4783 +- 0.204151
 SonicParanoid (fast) 0.9286 +- 0.1349070.5652 +- 0.202598
 SonicParanoid (fast) CORE 0.9 +- 0.1859420.3913 +- 0.199457
 SonicParanoid (ultra-fast) 0.8667 +- 0.2432880.2826 +- 0.184019
 SonicParanoid (ultra-fast) CORE 0.8182 +- 0.3223430.1957 +- 0.162127
 metaPhOrs 0.9355 +- 0.1223040.6304 +- 0.197269
 orthoinspector 1.30 (blast threshold 10-9) 0.9259 +- 0.1397050.5435 +- 0.20357
 phylomeDB 0.92 +- 0.1503970.5 +- 0.204344
 OMA Pairs (Refset5) 0.9333 +- 0.1262360.6087 +- 0.199457
SERCEggNOG 0.9968 +- 0.006302250.571 +- 0.0416679
 Ensembl Compara (e56) 0.9801 +- 0.01458480.6365 +- 0.0404948
 Ensembl Compara (e81) 0.9746 +- 0.01446940.8155 +- 0.0326562
 Hieranoid 2 0.9964 +- 0.005829970.7555 +- 0.036182
 InParanoid 0.9974 +- 0.005045050.714 +- 0.0380432
 InParanoidCore 0.995 +- 0.009678910.3708 +- 0.0406661
 OMA GETHOGs 0.9461 +- 0.01908270.9391 +- 0.0201318
 OMA GETHOGs 2.0 0.9765 +- 0.01344520.8801 +- 0.027351
 OMA Groups (RefSet5) 0.9911 +- 0.01734460.2057 +- 0.0340313
 OMA Groups 2.0 0.9811 +- 0.02114890.2878 +- 0.0381163
 OMA Pairs 2.0 0.9832 +- 0.01234550.7555 +- 0.036182
 PANTHER 8.0 (LDO only) 0.9941 +- 0.01146190.3127 +- 0.0390306
 PANTHER 8.0 (all) 0.9656 +- 0.01656760.8284 +- 0.0317411
 RBH / BBH 0.9941 +- 0.01156330.31 +- 0.0389355
 RSD 0.8 1e-5 Deluca 0.994 +- 0.01166650.3072 +- 0.0388392
 SonicParanoid (default) 0.9974 +- 0.004993620.7214 +- 0.0377426
 SonicParanoid (default) CORE 0.994 +- 0.01163190.3081 +- 0.0388713
 SonicParanoid (fast) 0.9974 +- 0.005110790.7048 +- 0.0384015
 SonicParanoid (fast) CORE 0.9939 +- 0.0119510.2998 +- 0.0385737
 SonicParanoid (ultra-fast) 0.9964 +- 0.006962550.5166 +- 0.0420716
 SonicParanoid (ultra-fast) CORE 0.9923 +- 0.01507660.2371 +- 0.0358053
 metaPhOrs 0.9978 +- 0.004265510.845 +- 0.0304671
 orthoinspector 1.30 (blast threshold 10-9) 0.9976 +- 0.004655570.774 +- 0.0352119
 phylomeDB 0.9977 +- 0.004480.8044 +- 0.0333926
 OMA Pairs (Refset5) 0.9887 +- 0.01105720.643 +- 0.0403365
SUMFEggNOG 0.95 +- 0.09551860.95 +- 0.0955186
 Ensembl Compara (e56) 0.95 +- 0.09551860.95 +- 0.0955186
 Ensembl Compara (e81) 0.95 +- 0.09551860.95 +- 0.0955186
 Hieranoid 2 0.95 +- 0.09551860.95 +- 0.0955186
 InParanoid 0.95 +- 0.09551860.95 +- 0.0955186
 InParanoidCore 0.9474 +- 0.1004070.9 +- 0.131481
 OMA GETHOGs 0.7451 +- 0.1691530.95 +- 0.0955186
 OMA GETHOGs 2.0 0.95 +- 0.09551860.95 +- 0.0955186
 OMA Groups (RefSet5) 0.9231 +- 0.1448540.6 +- 0.214707
 OMA Groups 2.0 0.9231 +- 0.1448540.6 +- 0.214707
 OMA Pairs 2.0 0.9487 +- 0.09790160.925 +- 0.115436
 PANTHER 8.0 (LDO only) 0.7941 +- 0.1922130.675 +- 0.205274
 PANTHER 8.0 (all) 0.7451 +- 0.1691530.95 +- 0.0955186
 RBH / BBH 0.95 +- 0.09551860.95 +- 0.0955186
 RSD 0.8 1e-5 Deluca 0.9412 +- 0.1118520.8 +- 0.175308
 SonicParanoid (default) 0.95 +- 0.09551860.95 +- 0.0955186
 SonicParanoid (default) CORE 0.95 +- 0.09551860.95 +- 0.0955186
 SonicParanoid (fast) 0.95 +- 0.09551860.95 +- 0.0955186
 SonicParanoid (fast) CORE 0.95 +- 0.09551860.95 +- 0.0955186
 SonicParanoid (ultra-fast) 0.95 +- 0.09551860.95 +- 0.0955186
 SonicParanoid (ultra-fast) CORE 0.95 +- 0.09551860.95 +- 0.0955186
 metaPhOrs 0.95 +- 0.09551860.95 +- 0.0955186
 orthoinspector 1.30 (blast threshold 10-9) 0.95 +- 0.09551860.95 +- 0.0955186
 phylomeDB 0.9412 +- 0.1118520.8 +- 0.175308
 OMA Pairs (Refset5) 0.9487 +- 0.09790160.925 +- 0.115436
TRFEEggNOG 0.9091 +- 0.169890.9091 +- 0.16989
 Ensembl Compara (e56) 0.8421 +- 0.2318790.7273 +- 0.263192
 Ensembl Compara (e81) 0.9048 +- 0.1775550.8636 +- 0.202803
 Hieranoid 2 0.9 +- 0.1859420.8182 +- 0.227931
 InParanoid 0.8947 +- 0.1951550.7727 +- 0.247655
 InParanoidCore 0.875 +- 0.2291770.6364 +- 0.28428
 OMA GETHOGs 0.9 +- 0.1859420.8182 +- 0.227931
 OMA GETHOGs 2.0 0.9 +- 0.1859420.8182 +- 0.227931
 OMA Groups (RefSet5) 0.8462 +- 0.2773750.5 +- 0.295481
 OMA Groups 2.0 0.8462 +- 0.2773750.5 +- 0.295481
 OMA Pairs 2.0 0.8947 +- 0.1951550.7727 +- 0.247655
 PANTHER 8.0 (LDO only) 0.8947 +- 0.1951550.7727 +- 0.247655
 PANTHER 8.0 (all) 0.7826 +- 0.2383970.8182 +- 0.227931
 RBH / BBH 0.8824 +- 0.21660.6818 +- 0.275253
 RSD 0.8 1e-5 Deluca 0.875 +- 0.2291770.6364 +- 0.28428
 SonicParanoid (default) 0.8947 +- 0.1951550.7727 +- 0.247655
 SonicParanoid (default) CORE 0.8462 +- 0.2773750.5 +- 0.295481
 SonicParanoid (fast) 0.8947 +- 0.1951550.7727 +- 0.247655
 SonicParanoid (fast) CORE 0.8462 +- 0.2773750.5 +- 0.295481
 SonicParanoid (ultra-fast) 0.8947 +- 0.1951550.7727 +- 0.247655
 SonicParanoid (ultra-fast) CORE 0.8462 +- 0.2773750.5 +- 0.295481
 metaPhOrs 0.8947 +- 0.1951550.7727 +- 0.247655
 orthoinspector 1.30 (blast threshold 10-9) 0.9 +- 0.1859420.8182 +- 0.227931
 phylomeDB 0.9 +- 0.1859420.8182 +- 0.227931
 OMA Pairs (Refset5) 0.8947 +- 0.1951550.7727 +- 0.247655
VATBEggNOG 0.9959 +- 0.008082480.8654 +- 0.0400905
 Ensembl Compara (e56) 0.9867 +- 0.01498710.7971 +- 0.0472303
 Ensembl Compara (e81) 0.9957 +- 0.008430050.8294 +- 0.0441744
 Hieranoid 2 0.9685 +- 0.0229370.7738 +- 0.0491374
 InParanoid 0.9847 +- 0.01585520.8115 +- 0.045936
 InParanoidCore 0.9916 +- 0.01335430.6373 +- 0.056465
 OMA GETHOGs 0.9956 +- 0.008540290.8187 +- 0.0452514
 OMA GETHOGs 2.0 0.9954 +- 0.008949710.781 +- 0.0485752
 OMA Groups (RefSet5) 0.9922 +- 0.01519350.4578 +- 0.0585141
 OMA Groups 2.0 0.9922 +- 0.01519350.4578 +- 0.0585141
 OMA Pairs 2.0 0.9953 +- 0.009158890.763 +- 0.0499423
 PANTHER 8.0 (LDO only) 0.993 +- 0.01361090.5117 +- 0.0587078
 PANTHER 8.0 (all) 0.9956 +- 0.008540290.8187 +- 0.0452514
 RBH / BBH 0.9948 +- 0.0100770.693 +- 0.0541726
 RSD 0.8 1e-5 Deluca 0.9925 +- 0.01462650.4758 +- 0.0586548
 SonicParanoid (default) 0.9857 +- 0.01485930.8671 +- 0.0398637
 SonicParanoid (default) CORE 0.9925 +- 0.01462650.4758 +- 0.0586548
 SonicParanoid (fast) 0.9857 +- 0.01485930.8671 +- 0.0398637
 SonicParanoid (fast) CORE 0.9925 +- 0.01462650.4758 +- 0.0586548
 SonicParanoid (ultra-fast) 0.9857 +- 0.01485930.8671 +- 0.0398637
 SonicParanoid (ultra-fast) CORE 0.9925 +- 0.01462650.4758 +- 0.0586548
 metaPhOrs 0.9947 +- 0.01045330.6679 +- 0.0553154
 orthoinspector 1.30 (blast threshold 10-9) 0.9858 +- 0.01479940.8707 +- 0.0394028
 phylomeDB 0.9954 +- 0.009073970.7702 +- 0.0494107
 OMA Pairs (Refset5) 0.9952 +- 0.009468440.7379 +- 0.0516519



Case Project pos. predictive value rate true positive rate Raw Data
TreeFamAEggNOG 0.9342 +- 0.003249640.5657 +- 0.00505699
 Ensembl Compara (e56) 0.9142 +- 0.004065150.4517 +- 0.00507746
 Ensembl Compara (e81) 0.9132 +- 0.00386150.5052 +- 0.00510097
 Hieranoid 2 0.9255 +- 0.00331750.6035 +- 0.00499069
 InParanoid 0.9285 +- 0.003186250.6317 +- 0.0049212
 InParanoidCore 0.9523 +- 0.003075080.4764 +- 0.00509555
 OMA GETHOGs 0.89 +- 0.003901730.5959 +- 0.00500656
 OMA GETHOGs 2.0 0.8355 +- 0.004427870.6096 +- 0.00497724
 OMA Groups (RefSet5) 0.9506 +- 0.003740670.3323 +- 0.00480592
 OMA Groups 2.0 0.946 +- 0.003593220.3895 +- 0.00497524
 OMA Pairs 2.0 0.903 +- 0.003774260.578 +- 0.00503876
 PANTHER 8.0 (LDO only) 0.9494 +- 0.003289360.4388 +- 0.00506287
 PANTHER 8.0 (all) 0.8743 +- 0.003845350.6765 +- 0.00477283
 RBH / BBH 0.948 +- 0.0031420.4926 +- 0.00510071
 RSD 0.8 1e-5 Deluca 0.9489 +- 0.003255550.4515 +- 0.00507723
 SonicParanoid (default) 0.9293 +- 0.00315590.6381 +- 0.00490282
 SonicParanoid (default) CORE 0.9501 +- 0.003223350.4515 +- 0.00507716
 SonicParanoid (fast) 0.928 +- 0.003220310.6227 +- 0.00494538
 SonicParanoid (fast) CORE 0.9492 +- 0.003296360.4387 +- 0.00506276
 SonicParanoid (ultra-fast) 0.9304 +- 0.003331940.5652 +- 0.00505771
 SonicParanoid (ultra-fast) CORE 0.9492 +- 0.003456890.3985 +- 0.00499496
 metaPhOrs 0.9484 +- 0.002648180.6894 +- 0.00472112
 orthoinspector 1.30 (blast threshold 10-9) 0.9268 +- 0.00316010.6551 +- 0.00484964
 phylomeDB 0.9491 +- 0.002768110.6232 +- 0.00494386
 OMA Pairs (Refset5) 0.9191 +- 0.003696090.5206 +- 0.0050969



Project # ortholog relations avg Schlicker Raw Data
EggNOG 736810.97185 +- 0.00082
Ensembl Compara (e56) 866050.9528 +- 0.0010
Ensembl Compara (e81) 976140.9471 +- 0.0010
Hieranoid 2 926360.95871 +- 0.00088
InParanoid 1131630.9295 +- 0.0011
InParanoidCore 769970.97461 +- 0.00077
OMA GETHOGs 1106830.9387 +- 0.0010
OMA GETHOGs 2.0 979890.9328 +- 0.0011
OMA Groups (RefSet5) 457460.98693 +- 0.00072
OMA Groups 2.0 574440.98353 +- 0.00074
OMA Pairs 2.0 867260.96585 +- 0.00085
PANTHER 8.0 (LDO only) 684570.97329 +- 0.00086
PANTHER 8.0 (all) 1202040.9370 +- 0.0010
RBH / BBH 883790.9585 +- 0.0010
RSD 0.8 1e-5 Deluca 812800.96287 +- 0.00093
SonicParanoid (default) 1118460.9323 +- 0.0010
SonicParanoid (default) CORE 812460.96435 +- 0.00091
SonicParanoid (fast) 1016580.9386 +- 0.0010
SonicParanoid (fast) CORE 731610.97097 +- 0.00085
SonicParanoid (ultra-fast) 913160.8621 +- 0.0016
SonicParanoid (ultra-fast) CORE 544410.97895 +- 0.00083
metaPhOrs 988290.9085 +- 0.0013
orthoinspector 1.30 (blast threshold 10-9) 1022510.95403 +- 0.00091
phylomeDB 893870.9524 +- 0.0010
OMA Pairs (Refset5) 791930.97378 +- 0.00079



Project # ortholog relations avg Schlicker Raw Data
EggNOG 779730.4991 +- 0.0016
Ensembl Compara (e56) 723870.4997 +- 0.0017
Ensembl Compara (e81) 908480.4940 +- 0.0015
Hieranoid 2 1041590.4933 +- 0.0014
InParanoid 1269030.4824 +- 0.0012
InParanoidCore 661630.5098 +- 0.0017
OMA GETHOGs 1231760.4815 +- 0.0012
OMA GETHOGs 2.0 1262620.4622 +- 0.0013
OMA Groups (RefSet5) 383410.5202 +- 0.0023
OMA Groups 2.0 477670.5156 +- 0.0021
OMA Pairs 2.0 889960.4910 +- 0.0015
PANTHER 8.0 (LDO only) 615950.5118 +- 0.0018
PANTHER 8.0 (all) 1747520.4658 +- 0.0011
RBH / BBH 740240.5076 +- 0.0016
RSD 0.8 1e-5 Deluca 630700.5121 +- 0.0018
SonicParanoid (default) 1204640.4833 +- 0.0013
SonicParanoid (default) CORE 616710.5125 +- 0.0018
SonicParanoid (fast) 1127600.4841 +- 0.0013
SonicParanoid (fast) CORE 574930.5126 +- 0.0019
SonicParanoid (ultra-fast) 1019620.4764 +- 0.0014
SonicParanoid (ultra-fast) CORE 483980.5124 +- 0.0020
metaPhOrs 1352070.4756 +- 0.0012
orthoinspector 1.30 (blast threshold 10-9) 1033980.4957 +- 0.0014
phylomeDB 1043020.4900 +- 0.0014
OMA Pairs (Refset5) 756210.5005 +- 0.0016